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Effect of Estrogen Plus Progestin on Stroke in Postmenopausal Women JAMA 289:2673-2684,2717, Wassertheil-Smoller,S.,et al, 2003 See this aricle in Pubmed Article Abstract Estrogen plus progestin increases the risk of ischemic stroke in generally healthy postmenopausal women. Excess risk for all strokes attributed to estrogen plus progestin appeared to be present in all subgroups of women examined.

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